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Echocardiographically measured epicardial fat predicts restenosis after coronary stenting.

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dc.contributor.authorPark, JS-
dc.contributor.authorChoi, BJ-
dc.contributor.authorChoi, SY-
dc.contributor.authorYoon, MH-
dc.contributor.authorHwang, GS-
dc.contributor.authorTahk, SJ-
dc.contributor.authorShin, JH-
dc.date.accessioned2014-05-19T05:42:27Z-
dc.date.available2014-05-19T05:42:27Z-
dc.date.issued2013-
dc.identifier.issn1401-7431-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/10004-
dc.description.abstractOBJECTIVE: Epicardial adipose tissue (EAT), deposited around subepicardial coronary vessels, may contribute directly to perivascular inflammation and smooth muscle cell proliferation. This study assessed the relationship between EAT and in-stent restenosis.



METHODS: Four hundred and seven patients had received successful coronary intervention. EAT thickness was measured by echocardiography. Angiographic follow-up was obtained between 6 months and 2 years. Restenosis was defined as target lesion revascularization (TLR). EAT thickness of patients was compared by TLR controlling for additional well-known predictors of restenosis. The TLR-free survival analysis according to EAT thickness was estimated using the Kaplan-Meier method and the differences between groups were assessed by the log-rank test.



RESULTS: Median EAT thickness was significantly increased in patients undergoing TLR compared with those without restenosis (3.7 vs. 3.0 mm, p = 0.001). EAT thickness was one of the independent factors associated with restenosis (Odds ratio = 1.19, 95% confidence interval = 1.01-1.33, p = 0.007). The TLR-free survival of patients with thick EAT was significantly worse than patients with thin EAT (log-rank p = 0.001).



CONCLUSIONS: EAT thickness is related with restenosis and may provide additional information for future restenosis.
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dc.language.isoen-
dc.subject.MESHAdipose Tissue-
dc.subject.MESHAdiposity-
dc.subject.MESHAged-
dc.subject.MESHCoronary Restenosis-
dc.subject.MESHEchocardiography-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPercutaneous Coronary Intervention-
dc.subject.MESHPostoperative Complications-
dc.subject.MESHStents-
dc.titleEchocardiographically measured epicardial fat predicts restenosis after coronary stenting.-
dc.typeArticle-
dc.identifier.pmid23937273-
dc.identifier.urlhttp://informahealthcare.com/doi/abs/10.3109/14017431.2013.824604-
dc.contributor.affiliatedAuthor박, 진선-
dc.contributor.affiliatedAuthor최, 병주-
dc.contributor.affiliatedAuthor최, 소연-
dc.contributor.affiliatedAuthor윤, 명호-
dc.contributor.affiliatedAuthor황, 교승-
dc.contributor.affiliatedAuthor탁, 승제-
dc.contributor.affiliatedAuthor신, 준한-
dc.type.localJournal Papers-
dc.identifier.doi10.3109/14017431.2013.824604-
dc.citation.titleScandinavian cardiovascular journal : SCJ-
dc.citation.volume47-
dc.citation.number5-
dc.citation.date2013-
dc.citation.startPage297-
dc.citation.endPage302-
dc.identifier.bibliographicCitationScandinavian cardiovascular journal : SCJ, 47(5). : 297-302, 2013-
dc.identifier.eissn1651-2006-
dc.relation.journalidJ014017431-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Cardiology
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