Graphene-incorporated chitosan substrata for adhesion and differentiation of human mesenchymal stem cells.

Abstract

A simple method that uses graphene to fabricate nanotopographic substrata was reported for stem cell engineering. Graphene-incorporated chitosan substrata promoted adhesion and differentiation of human mesenchymal stem cells (hMSCs). In addition, we proposed that nanotopographic cues of the substrata could enhance cell–cell and cell–material interactions for promoting functions of hMSCs.