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Hemophagocytosis by leukemic blasts in B lymphoblastic leukemia with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1): a case report.
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Park, JE | - |
| dc.contributor.author | Park, IJ | - |
| dc.contributor.author | Lim, YA | - |
| dc.contributor.author | Lee, WG | - |
| dc.contributor.author | Cho, SR | - |
| dc.date.accessioned | 2014-06-02 | - |
| dc.date.available | 2014-06-02 | - |
| dc.date.issued | 2013 | - |
| dc.identifier.issn | 0091-7370 | - |
| dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/10314 | - |
| dc.description.abstract | Blasts showing hemophagocytosis have been very rarely reported in acute lymphoblastic leukemia. We report a pediatric case of B lymphoblastic leukemia (BLL) with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1) showing erythrophagocytosis and thrombophagocytosis by leukemic blasts. About 4% of the leukemic blasts in marrow aspirate smears showed phagocytosis of erythrocytes, platelets, or nuclear remnants in a 3-year-old Korean boy with a diagnosis of BLL. Conventional cytogenetics and molecular analysis revealed the presence of t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1). The patient responded well to chemotherapy and is in a state of complete remission. | - |
| dc.format | text/plain | - |
| dc.language.iso | en | - |
| dc.subject.MESH | Child, Preschool | - |
| dc.subject.MESH | Chromosomes, Human, Pair 12 | - |
| dc.subject.MESH | Chromosomes, Human, Pair 13 | - |
| dc.subject.MESH | Core Binding Factor Alpha 2 Subunit | - |
| dc.subject.MESH | Cytogenetic Analysis | - |
| dc.subject.MESH | Erythrocytes | - |
| dc.subject.MESH | Humans | - |
| dc.subject.MESH | Immunophenotyping | - |
| dc.subject.MESH | Male | - |
| dc.subject.MESH | Myeloid Progenitor Cells | - |
| dc.subject.MESH | Oncogene Proteins, Fusion | - |
| dc.subject.MESH | Phagocytosis | - |
| dc.subject.MESH | Precursor Cell Lymphoblastic Leukemia-Lymphoma | - |
| dc.subject.MESH | Republic of Korea | - |
| dc.subject.MESH | Translocation, Genetic | - |
| dc.title | Hemophagocytosis by leukemic blasts in B lymphoblastic leukemia with t(12;21)(p13;q22); TEL-AML1 (ETV6-RUNX1): a case report. | - |
| dc.type | Article | - |
| dc.identifier.pmid | 23694795 | - |
| dc.identifier.url | http://www.annclinlabsci.org/cgi/pmidlookup?view=long&pmid=23694795 | - |
| dc.contributor.affiliatedAuthor | 박, 준은 | - |
| dc.contributor.affiliatedAuthor | 박, 일중 | - |
| dc.contributor.affiliatedAuthor | 임, 영애 | - |
| dc.contributor.affiliatedAuthor | 이, 위교 | - |
| dc.contributor.affiliatedAuthor | 조, 성란 | - |
| dc.type.local | Journal Papers | - |
| dc.citation.title | Annals of clinical and laboratory science | - |
| dc.citation.volume | 43 | - |
| dc.citation.number | 2 | - |
| dc.citation.date | 2013 | - |
| dc.citation.startPage | 186 | - |
| dc.citation.endPage | 189 | - |
| dc.identifier.bibliographicCitation | Annals of clinical and laboratory science, 43(2). : 186-189, 2013 | - |
| dc.identifier.eissn | 1550-8080 | - |
| dc.relation.journalid | J000917370 | - |
- Appears in Collections:
- Journal Papers > School of Medicine / Graduate School of Medicine > Pediatrics & Adolescent Medicine
Journal Papers > School of Medicine / Graduate School of Medicine > Laboratory Medicine
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