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Hyperosmotic polydixylitol for crossing the blood brain barrier and efficient nucleic acid delivery.

Authors
Garg, P | Pandey, S | Seonwoo, H | Yeom, S | Choung, YH  | Cho, CS | Choung, PH | Hoon Chung, J
Citation
Chemical communications (Cambridge, England), 51(17). : 3645-3648, 2015
Journal Title
Chemical communications (Cambridge, England)
ISSN
1359-73451364-548X
Abstract
Here, we introduce a polydixylitol based highly osmotic polymer that not only transmigrates the BBB by intra-arterial infusion of osmotic polyol but also triggers cellular uptake via modulation of caveolae mediated endocytosis.
MeSH

DOI
10.1039/c4cc09871d
PMID
25645149
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Otolaryngology
Ajou Authors
정, 연훈
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