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The paradigm of immune escape by SARS-CoV-2 variants and strategies for repositioning subverted mAbs against escaped VOCs
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Shah, M | - |
| dc.contributor.author | Woo, HG | - |
| dc.date.accessioned | 2023-02-13T06:23:24Z | - |
| dc.date.available | 2023-02-13T06:23:24Z | - |
| dc.date.issued | 2022 | - |
| dc.identifier.issn | 1525-0016 | - |
| dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/24568 | - |
| dc.description.abstract | The perpetual emergence of SARS-CoV-2 variants is a serious issue that makes it difficult for the therapeutic antibodies and vaccines to end the COVID-19 pandemic. This article discusses the trend of increasing host fitness and immune escape by the virus and how to devise computational strategies for antibodies design and their affinity maturation against emerging SARS-CoV-2 variants. | - |
| dc.language.iso | en | - |
| dc.subject.MESH | Antibodies, Monoclonal | - |
| dc.subject.MESH | Antibodies, Neutralizing | - |
| dc.subject.MESH | Antibodies, Viral | - |
| dc.subject.MESH | COVID-19 | - |
| dc.subject.MESH | Humans | - |
| dc.subject.MESH | Neutralization Tests | - |
| dc.subject.MESH | Pandemics | - |
| dc.subject.MESH | SARS-CoV-2 | - |
| dc.subject.MESH | Spike Glycoprotein, Coronavirus | - |
| dc.subject.MESH | Viral Envelope Proteins | - |
| dc.title | The paradigm of immune escape by SARS-CoV-2 variants and strategies for repositioning subverted mAbs against escaped VOCs | - |
| dc.type | Article | - |
| dc.identifier.pmid | 36087577 | - |
| dc.identifier.url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9462941 | - |
| dc.contributor.affiliatedAuthor | Shah, M | - |
| dc.contributor.affiliatedAuthor | Woo, HG | - |
| dc.type.local | Journal Papers | - |
| dc.identifier.doi | 10.1016/j.ymthe.2022.08.020 | - |
| dc.citation.title | Molecular therapy | - |
| dc.citation.volume | 30 | - |
| dc.citation.number | 10 | - |
| dc.citation.date | 2022 | - |
| dc.citation.startPage | 3101 | - |
| dc.citation.endPage | 3105 | - |
| dc.identifier.bibliographicCitation | Molecular therapy, 30(10). : 3101-3105, 2022 | - |
| dc.identifier.eissn | 1525-0024 | - |
| dc.relation.journalid | J015250016 | - |
- Appears in Collections:
- Journal Papers > School of Medicine / Graduate School of Medicine > Physiology
- Files in This Item:
- 36087577.pdfDownload
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