Cited 0 times in
Deep brain stimulation in Parkinson disease with valosin-containing protein gene mutation
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, YS | - |
dc.contributor.author | Park, DG | - |
dc.contributor.author | Kim, MS | - |
dc.contributor.author | Yoon, JH | - |
dc.date.accessioned | 2023-08-24T05:34:58Z | - |
dc.date.available | 2023-08-24T05:34:58Z | - |
dc.date.issued | 2023 | - |
dc.identifier.issn | 1351-5101 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/26202 | - |
dc.description.abstract | Background and purpose: Mutations in the gene encoding valosin-containing protein (VCP) are related to myriad medical conditions, including familial amyotrophic lateral sclerosis, inclusion body myopathy, and frontotemporal dementia. There are several reports of a link between these mutations and early onset Parkinson disease (PD). Case description: We report a 53-year-old PD patient with VCP mutation who later developed motor complications, thus receiving subthalamic nucleus deep brain stimulation (DBS) at the age of 56 years. However, myopathy emerged 1.5 years after surgery. Conclusions: With the phenotype variability of VCP, DBS should be carefully evaluated, considering the possible unfavorable long-term outcomes due to other symptoms of this mutation. | - |
dc.language.iso | en | - |
dc.subject.MESH | Cell Cycle Proteins | - |
dc.subject.MESH | Deep Brain Stimulation | - |
dc.subject.MESH | Frontotemporal Dementia | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Muscular Diseases | - |
dc.subject.MESH | Mutation | - |
dc.subject.MESH | Osteitis Deformans | - |
dc.subject.MESH | Parkinson Disease | - |
dc.subject.MESH | Valosin Containing Protein | - |
dc.title | Deep brain stimulation in Parkinson disease with valosin-containing protein gene mutation | - |
dc.type | Article | - |
dc.identifier.pmid | 37170789 | - |
dc.subject.keyword | deep brain stimulation | - |
dc.subject.keyword | myopathy | - |
dc.subject.keyword | next generation sequencing | - |
dc.subject.keyword | Parkinson disease | - |
dc.subject.keyword | valosin-containing protein | - |
dc.subject.keyword | VCP | - |
dc.contributor.affiliatedAuthor | Park, DG | - |
dc.contributor.affiliatedAuthor | Yoon, JH | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.1111/ene.15824 | - |
dc.citation.title | European journal of neurology | - |
dc.citation.volume | 30 | - |
dc.citation.number | 8 | - |
dc.citation.date | 2023 | - |
dc.citation.startPage | 2583 | - |
dc.citation.endPage | 2586 | - |
dc.identifier.bibliographicCitation | European journal of neurology, 30(8). : 2583-2586, 2023 | - |
dc.embargo.liftdate | 9999-12-31 | - |
dc.embargo.terms | 9999-12-31 | - |
dc.identifier.eissn | 1468-1331 | - |
dc.relation.journalid | J013515101 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.