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Clinical Relevance of Serum CC16 in Adult Asthma
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.advisor | 박, 해심 | - |
| dc.contributor.author | 정, 창규 | - |
| dc.date.accessioned | 2023-11-16T05:43:58Z | - |
| dc.date.available | 2023-11-16T05:43:58Z | - |
| dc.date.issued | 2023 | - |
| dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/26862 | - |
| dc.language.iso | ko | - |
| dc.title | Clinical Relevance of Serum CC16 in Adult Asthma | - |
| dc.title.alternative | 성인 천식에서 혈청 CC16 수준의 임상적 유용성 | - |
| dc.type | Thesis | - |
| dc.identifier.url | http://dcoll.ajou.ac.kr:9080/dcollection/jsp/common/DcLoOrgPer.jsp?sItemId=000000032667 | - |
| dc.subject.keyword | CC16 | - |
| dc.subject.keyword | Asthma | - |
| dc.subject.keyword | Airway reversibility | - |
| dc.subject.keyword | Lung function | - |
| dc.subject.keyword | Epithelial cells | - |
| dc.subject.keyword | 천식 | - |
| dc.subject.keyword | 기도 가역성 | - |
| dc.subject.keyword | 폐 기능 | - |
| dc.subject.keyword | 기도 상피 세포 | - |
| dc.subject.keyword | 생체지표 | - |
| dc.description.degree | Doctor | - |
| dc.contributor.department | 대학원 의학과 | - |
| dc.contributor.affiliatedAuthor | 정, 창규 | - |
| dc.date.awarded | 2023 | - |
| dc.type.local | Theses | - |
| dc.citation.date | 2023 | - |
| dc.embargo.liftdate | 9999-12-31 | - |
| dc.embargo.terms | 9999-12-31 | - |
| dc.description.tableOfContents | I. INTRODUCTION 1
A. Unmet needs in asthma 1 B. The role of epithelial cells in asthma 2 C. Reactive oxygen species (ROS) in asthma 3 D. Club cell 16-kDa secretory protein (CC16) 4 E. Aims of the thesis 5 II. MATERIALS AND METHODS 6 A. Study subjects and clinical evaluation 6 B. In vitro experiments 8 C. Statistical analysis 10 III. RESULTS 11 A. Study subjects and clinical/laboratory characteristics 11 B. In vitro experiments 13 IV. DISCUSSION 16 A. Serum CC16 level is a predictor for airway reversibility and lower lung function 16 B. CC16 as a therapeutic target for asthma 17 C. Anti-inflammatory and anti-oxidant effects of CC16 on HAECs 18 D. CC16 as a diagnostic biomarker for asthma 19 E. Limitations of the study 20 V. CONCLUSION 21 VI. REFERENCES 22 제2언어초록 48 | - |
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