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The efficacy of preoperative PET/CT for prediction of curability in surgery for locally advanced gastric carcinoma.
DC Field | Value | Language |
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dc.contributor.author | Hur, H | - |
dc.contributor.author | Kim, SH | - |
dc.contributor.author | Kim, W | - |
dc.contributor.author | Song, KY | - |
dc.contributor.author | Park, CH | - |
dc.contributor.author | Jeon, HM | - |
dc.date.accessioned | 2011-05-31T02:26:40Z | - |
dc.date.available | 2011-05-31T02:26:40Z | - |
dc.date.issued | 2010 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/2737 | - |
dc.description.abstract | BACKGROUND: The benefits of preoperative 18FDG-PET/CT for gastric cancer remain uncertain. The aim of this study was to investigate the effects of preoperative 18FDG-PET/CT on the surgical strategy for locally advanced gastric cancer retrospectively.
METHODS: From January 2007 to November 2008, 18FDG-PET/CT was performed in 142 patients who had been diagnosed with advanced gastric cancer by computed tomography or gastrofiberscope findings. RESULTS: Detection rates were 88.7% (126/142) for primary tumors and 24.6% (35/142) for local lymph nodes (LN). Nine patients with metastatic lesions underwent induction chemotherapy without operation. Of 133 patients subjected to operation, positive FDG uptake in primary tumors (p=0.047) and local lymph nodes (p<0.001) was related to non-curable operations. The mean standard uptake value (SUV) of primary tumors of patients who underwent non-curable operations was significantly higher than that of patients with curable operations (p=0.001). When the SUV was greater than 5 and FDG uptake of LN was positive, non-curable operations were predicted with a sensitivity of 35.2%, a specificity of 91.0% and an accuracy of 76.7%. CONCLUSIONS: High SUV of the primary tumor and positive FDG uptake in local lymph nodes at PET/CT could predict non-curative resection in locally advanced gastric cancer. Therefore, information from preoperative PET/CT can help physician decisions regarding other modalities without laparotomy. | - |
dc.language.iso | en | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorodeoxyglucose F18 | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Gastrectomy | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Positron-Emission Tomography | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Preoperative Care | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Radiopharmaceuticals | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sensitivity and Specificity | - |
dc.subject.MESH | Stomach Neoplasms | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | The efficacy of preoperative PET/CT for prediction of curability in surgery for locally advanced gastric carcinoma. | - |
dc.type | Article | - |
dc.identifier.pmid | 20932345 | - |
dc.identifier.url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2964718/ | - |
dc.contributor.affiliatedAuthor | 허, 훈 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.1186/1477-7819-8-86 | - |
dc.citation.title | World journal of surgical oncology | - |
dc.citation.volume | 8 | - |
dc.citation.date | 2010 | - |
dc.citation.startPage | 86 | - |
dc.citation.endPage | 86 | - |
dc.identifier.bibliographicCitation | World journal of surgical oncology, 8. : 86-86, 2010 | - |
dc.identifier.eissn | 1477-7819 | - |
dc.relation.journalid | J014777819 | - |
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