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Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jew, SS | - |
dc.contributor.author | Yoon, CH | - |
dc.contributor.author | Lim, DY | - |
dc.contributor.author | Kim, H | - |
dc.contributor.author | Mook-Jung, I | - |
dc.contributor.author | Jung, MW | - |
dc.contributor.author | Choi, H | - |
dc.contributor.author | Jung, YH | - |
dc.contributor.author | Park, HG | - |
dc.date.accessioned | 2011-08-18T01:45:07Z | - |
dc.date.available | 2011-08-18T01:45:07Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/3780 | - |
dc.description.abstract | 8 Semi-synthetic derivatives of asiatic acid were prepared and their protective effect against A beta-induced neurotoxicity was evaluated. Among them, asiatic acid (2), and 4, 16 showed 97, 92 and 87% of protective effect, respectively. | - |
dc.language.iso | en | - |
dc.subject.MESH | Alzheimer Disease | - |
dc.subject.MESH | Amyloid beta-Peptides | - |
dc.subject.MESH | Cell Death | - |
dc.subject.MESH | Cell Line | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Molecular Structure | - |
dc.subject.MESH | Neuroprotective Agents | - |
dc.subject.MESH | Pentacyclic Triterpenes | - |
dc.subject.MESH | Peptide Fragments | - |
dc.subject.MESH | Plants, Medicinal | - |
dc.subject.MESH | Structure-Activity Relationship | - |
dc.subject.MESH | Triterpenes | - |
dc.title | Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity. | - |
dc.type | Article | - |
dc.identifier.pmid | 10673093 | - |
dc.identifier.url | http://linkinghub.elsevier.com/retrieve/pii/S0960894X99006587 | - |
dc.contributor.affiliatedAuthor | 묵, 인희 | - |
dc.contributor.affiliatedAuthor | 정, 민환 | - |
dc.type.local | Journal Papers | - |
dc.citation.title | Bioorganic & medicinal chemistry letters | - |
dc.citation.volume | 10 | - |
dc.citation.number | 2 | - |
dc.citation.date | 2000 | - |
dc.citation.startPage | 119 | - |
dc.citation.endPage | 121 | - |
dc.identifier.bibliographicCitation | Bioorganic & medicinal chemistry letters, 10(2). : 119-121, 2000 | - |
dc.identifier.eissn | 1464-3405 | - |
dc.relation.journalid | J00960894X | - |
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