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Structure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.

DC Field Value Language
dc.contributor.authorJew, SS-
dc.contributor.authorYoon, CH-
dc.contributor.authorLim, DY-
dc.contributor.authorKim, H-
dc.contributor.authorMook-Jung, I-
dc.contributor.authorJung, MW-
dc.contributor.authorChoi, H-
dc.contributor.authorJung, YH-
dc.contributor.authorPark, HG-
dc.date.accessioned2011-08-18T01:45:07Z-
dc.date.available2011-08-18T01:45:07Z-
dc.date.issued2000-
dc.identifier.issn0960-894X-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/3780-
dc.description.abstract8 Semi-synthetic derivatives of asiatic acid were prepared and their protective effect against A beta-induced neurotoxicity was evaluated. Among them, asiatic acid (2), and 4, 16 showed 97, 92 and 87% of protective effect, respectively.-
dc.language.isoen-
dc.subject.MESHAlzheimer Disease-
dc.subject.MESHAmyloid beta-Peptides-
dc.subject.MESHCell Death-
dc.subject.MESHCell Line-
dc.subject.MESHHumans-
dc.subject.MESHMolecular Structure-
dc.subject.MESHNeuroprotective Agents-
dc.subject.MESHPentacyclic Triterpenes-
dc.subject.MESHPeptide Fragments-
dc.subject.MESHPlants, Medicinal-
dc.subject.MESHStructure-Activity Relationship-
dc.subject.MESHTriterpenes-
dc.titleStructure-activity relationship study of asiatic acid derivatives against beta amyloid (A beta)-induced neurotoxicity.-
dc.typeArticle-
dc.identifier.pmid10673093-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0960894X99006587-
dc.contributor.affiliatedAuthor묵, 인희-
dc.contributor.affiliatedAuthor정, 민환-
dc.type.localJournal Papers-
dc.citation.titleBioorganic & medicinal chemistry letters-
dc.citation.volume10-
dc.citation.number2-
dc.citation.date2000-
dc.citation.startPage119-
dc.citation.endPage121-
dc.identifier.bibliographicCitationBioorganic & medicinal chemistry letters, 10(2). : 119-121, 2000-
dc.identifier.eissn1464-3405-
dc.relation.journalidJ00960894X-
Appears in Collections:
Journal Papers > Research Organization > Brain Disease Research Center
Journal Papers > Research Organization > Institute for Medical Sciences
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