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6-arylamino-5,8-quinolinediones and 7-arylamino-5,8-isoquinolinediones as inhibitors of endothelium-dependent vasorelaxation.

DC Field Value Language
dc.contributor.authorRyu, CK-
dc.contributor.authorJung, SH-
dc.contributor.authorLee, JA-
dc.contributor.authorKim, HJ-
dc.contributor.authorLee, SH-
dc.contributor.authorChung, JH-
dc.date.accessioned2011-09-02T01:07:09Z-
dc.date.available2011-09-02T01:07:09Z-
dc.date.issued1999-
dc.identifier.issn0960-894X-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/3996-
dc.description.abstract6-Arylamino-5,8-quinolinediones 3 and 7-arylamino-5,8-isoquinolinediones 4 were synthesized as inhibitors of endothelium-dependent vasorelaxation. The quinones inhibited the vasorelaxation of rat aorta with the endothelium. Among them, the quinones 3a, 3b, 3f, 4b, 4d and 4g strongly inhibited the vasorelaxation.-
dc.language.isoen-
dc.subject.MESHAnimals-
dc.subject.MESHAorta-
dc.subject.MESHEndothelium, Vascular-
dc.subject.MESHMuscle Relaxation-
dc.subject.MESHQuinolines-
dc.subject.MESHRats-
dc.subject.MESHStructure-Activity Relationship-
dc.title6-arylamino-5,8-quinolinediones and 7-arylamino-5,8-isoquinolinediones as inhibitors of endothelium-dependent vasorelaxation.-
dc.typeArticle-
dc.identifier.pmid10498190-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0960894X99004114-
dc.contributor.affiliatedAuthor이, 수환-
dc.type.localJournal Papers-
dc.citation.titleBioorganic & medicinal chemistry letters-
dc.citation.volume9-
dc.citation.number17-
dc.citation.date1999-
dc.citation.startPage2469-
dc.citation.endPage2472-
dc.identifier.bibliographicCitationBioorganic & medicinal chemistry letters, 9(17). : 2469-2472, 1999-
dc.identifier.eissn1464-3405-
dc.relation.journalidJ00960894X-
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Journal Papers > School of Medicine / Graduate School of Medicine > Physiology
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