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6-arylamino-5,8-quinolinediones and 7-arylamino-5,8-isoquinolinediones as inhibitors of endothelium-dependent vasorelaxation.
DC Field | Value | Language |
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dc.contributor.author | Ryu, CK | - |
dc.contributor.author | Jung, SH | - |
dc.contributor.author | Lee, JA | - |
dc.contributor.author | Kim, HJ | - |
dc.contributor.author | Lee, SH | - |
dc.contributor.author | Chung, JH | - |
dc.date.accessioned | 2011-09-02T01:07:09Z | - |
dc.date.available | 2011-09-02T01:07:09Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/3996 | - |
dc.description.abstract | 6-Arylamino-5,8-quinolinediones 3 and 7-arylamino-5,8-isoquinolinediones 4 were synthesized as inhibitors of endothelium-dependent vasorelaxation. The quinones inhibited the vasorelaxation of rat aorta with the endothelium. Among them, the quinones 3a, 3b, 3f, 4b, 4d and 4g strongly inhibited the vasorelaxation. | - |
dc.language.iso | en | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Aorta | - |
dc.subject.MESH | Endothelium, Vascular | - |
dc.subject.MESH | Muscle Relaxation | - |
dc.subject.MESH | Quinolines | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Structure-Activity Relationship | - |
dc.title | 6-arylamino-5,8-quinolinediones and 7-arylamino-5,8-isoquinolinediones as inhibitors of endothelium-dependent vasorelaxation. | - |
dc.type | Article | - |
dc.identifier.pmid | 10498190 | - |
dc.identifier.url | http://linkinghub.elsevier.com/retrieve/pii/S0960894X99004114 | - |
dc.contributor.affiliatedAuthor | 이, 수환 | - |
dc.type.local | Journal Papers | - |
dc.citation.title | Bioorganic & medicinal chemistry letters | - |
dc.citation.volume | 9 | - |
dc.citation.number | 17 | - |
dc.citation.date | 1999 | - |
dc.citation.startPage | 2469 | - |
dc.citation.endPage | 2472 | - |
dc.identifier.bibliographicCitation | Bioorganic & medicinal chemistry letters, 9(17). : 2469-2472, 1999 | - |
dc.identifier.eissn | 1464-3405 | - |
dc.relation.journalid | J00960894X | - |
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