Cited 0 times in
Simultaneous measurement of 23 plasma cytokines in late-life depression.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, KS | - |
dc.contributor.author | Chung, JH | - |
dc.contributor.author | Lee, KH | - |
dc.contributor.author | Shin, MJ | - |
dc.contributor.author | Oh, BH | - |
dc.contributor.author | Lee, SH | - |
dc.contributor.author | Hong, CH | - |
dc.date.accessioned | 2010-12-06T02:18:55Z | - |
dc.date.available | 2010-12-06T02:18:55Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 1590-1874 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/427 | - |
dc.description.abstract | According to the cytokine hypothesis of depression, cytokines play key roles in the behavioral, neuroendocrinal, and neurochemical features of depression. In this study, we used a bioplex assay to simultaneously measure the levels of 23 plasma cytokines in 18 patients with late-life depression and 38 normal controls, and these levels were compared between the two groups. The plasma interleukin-1alpha (IL-1alpha) levels were found to be significantly different between the two groups. After adjusting for age, gender, low-density lipoprotein cholesterol, and triglyceride, the plasma IL-1alpha levels were significantly higher in the patients with late-life depression than in the normal control subjects. Thus, this study provides preliminary evidence that plasma IL-1alpha may play important roles in the pathogenesis of late-life depression. | - |
dc.language.iso | en | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Cytokines | - |
dc.subject.MESH | Depression | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Plasma | - |
dc.title | Simultaneous measurement of 23 plasma cytokines in late-life depression. | - |
dc.type | Article | - |
dc.identifier.pmid | 19484185 | - |
dc.contributor.affiliatedAuthor | 홍, 창형 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.1007/s10072-009-0091-1 | - |
dc.citation.title | Neurological sciences | - |
dc.citation.volume | 30 | - |
dc.citation.number | 5 | - |
dc.citation.date | 2009 | - |
dc.citation.startPage | 435 | - |
dc.citation.endPage | 438 | - |
dc.identifier.bibliographicCitation | Neurological sciences, 30(5). : 435-438, 2009 | - |
dc.identifier.eissn | 1590-3478 | - |
dc.relation.journalid | J015901874 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.