POEMS syndrome에서의 18F-FDG PET/CT 소견

Abstract

POEMS syndrome is a rare disorder, also known as Crow-Fukase, PEP or Takatsuki syndrome. The acronym,

POEMS, represents polyneuropathy, organomegaly, endocrinopathy, M protein and skin change.1,2) However, there

are associated features not included in the acronym such as sclerotic bone lesions, Castleman disease,

papilledema, thromobocytosis, peripheral edema, ascites, effusion, polycythemia, fatigue and clubbing.1-5) In most

cases, osseous lesions in POEMS syndrome present as an isolated sclerotic deposit and that reveal as

osteosclerotic myeloma.6,7) Several cases of 18F-FDG PET in multiple myeloma involvements were reported,8) but

there was no previous literature that reported FDG PET findings in POEMS syndrome. We describe here a

66-year-old patient with POEMS syndrome who underwent 18F-FDG PET/CT image.