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Significance of Erythrocyte Sedimentation Rate and C-reactive Protein as Predictive Factors for Prognosis in Non-metastatic Renal Cell Carcinoma

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dc.contributor.author김, 영균-
dc.contributor.author김, 선일-
dc.contributor.author김, 세중-
dc.date.accessioned2011-11-22-
dc.date.available2011-11-22-
dc.date.issued2006-
dc.identifier.issn0494-4747-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/4491-
dc.description.abstractPurpose: This study was performed to investigate the significance of preoperative erythrocyte sedimentation rate(ESR) and C-reactive protein(CRP) and postoperative ESR and CRP nadir as predictive factors for prognosis in patients with non-metastatic renal cell carcinoma(RCC).
Materials & Methods: In 66 patients with non-metastatic RCC for whom ESR and CRP could be measured before radical nephrectomy and during follow-up, the preoperative ESR, preoperative CRP, postoperative ESR nadir and postoperative CRP nadir were compared with the clinicopathological variables.
Results: Patients with elevated preoperative ESR or CRP levels were more likely to have tumors with adverse features, including larger tumor size, higher T stage, higher nuclear grade and more frequent metastasis at follow-up, as compared to those patients with lower preoperative ESR or CRP levels, respectively. Patients with an elevated postoperative CRP nadir developed metastasis more frequently at follow-up as compared to those patients with a lower level of postoperative CRP nadir. The univariate analyses identified tumor size, T stage, preoperative ESR, preoperative CRP and postoperative CRP nadir as significant prognostic factors for recurrence-free survival
Conclusion: Elevated preoperative ESR, preoperative CRP and postoperative CRP nadir are associated with a worse prognosis and a higher recurrence rate in patients with non-metastatic RCC, suggesting that ESR and CRP are valuable prognostic indicators in RCC.
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dc.formattext/plain-
dc.language.isoko-
dc.titleSignificance of Erythrocyte Sedimentation Rate and C-reactive Protein as Predictive Factors for Prognosis in Non-metastatic Renal Cell Carcinoma-
dc.title.alternative비전이성 신세포암의 예후 예측인자로서 적혈구침강속도와 C반응단백의 의의-
dc.typeArticle-
dc.identifier.urlhttp://pdf.medrang.co.kr/Kju/047/Kju047-10-06.pdf-
dc.subject.keywordRenal cell carcinoma-
dc.subject.keywordErythrocyte sedimentation rate-
dc.subject.keywordC- reactive protein-
dc.subject.keywordPrognosis-
dc.contributor.affiliatedAuthor김, 선일-
dc.contributor.affiliatedAuthor김, 세중-
dc.type.localJournal Papers-
dc.identifier.doi10.4111/kju.2006.47.10.1059-
dc.citation.titleKorean journal of urology-
dc.citation.volume47-
dc.citation.number10-
dc.citation.date2006-
dc.citation.startPage1059-
dc.citation.endPage1064-
dc.identifier.bibliographicCitationKorean journal of urology, 47(10). : 1059-1064, 2006-
dc.relation.journalidJ004944747-
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Journal Papers > School of Medicine / Graduate School of Medicine > Urology
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