Retrograde pulmonary arteriography via brachial artery was used to clarify the anatomy of pulmonary artery and descending aorta in 4 neonates with ductus-dependent cyanotic heart diseases. The age ranged from 28 to 37 days (30.8±3.7 days). The suspected diagnosis was pulmonary atresia with ventricular septal defect in 2 neonates, pulmonary atresia with intact ventricular septum in one, and tricuspid atresia with pulmonary atresia in the other patient. All cases had been infused with prostaglandin El, A retrograde pulmonary arteriogram provided adequate diagnostic informations by visualizing the presence of ductus connected to pulmonary artery. There was no significant complication during the procedure. Retrograde pulmonary arteriography is a minimally invasive, rapid, and safe procedure that can provide adequate angiographic information without the need for cardiac catheterization in neonates with ductus-dependent cyanotic heart disease who are hemodynamically compromized.