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Fully covered, retrievable self-expanding metal stents (Niti-S) in palliation of malignant dysphagia: long-term results of a prospective study.

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dc.contributor.authorChoi, SJ-
dc.contributor.authorKim, JH-
dc.contributor.authorChoi, JW-
dc.contributor.authorLim, SG-
dc.contributor.authorShin, SJ-
dc.contributor.authorLee, KM-
dc.contributor.authorLee, KJ-
dc.date.accessioned2012-04-19T23:38:43Z-
dc.date.available2012-04-19T23:38:43Z-
dc.date.issued2011-
dc.identifier.issn0036-5521-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/6439-
dc.description.abstractBACKGROUND: In the palliative treatment of malignant dysphagia, fully covered, retrievable metal stents are not commonly used, mainly due to the high risk of migration. Therefore, we performed a prospective study to evaluate the clinical efficacy of a fully covered, retrievable self-expanding metal stent (Niti-S).



METHOD: Between October 1998 and February 2009, 100 consecutive patients with malignant esophageal obstruction treated with the fully covered Niti-S stent (Niti-S, Taewoong Medical, Seoul, South Korea) were included. Data collected contained functional outcome, feasibility of endoscopic stent retrieval, recurrent dysphagia, complications, and survival.



RESULT: At 4 weeks after stent placement, dysphagia significantly improved in all patients (p = 0.000). Recurrent dysphagia occurred in 19 of 100 patients treated with Niti-S stents (19%) mainly due to tumor overgrowth (7/100, 7%), stent migration (6/100, 6%), and food impaction (6/100, 6%). Endoscopic stent retrieval was successful in all the attempted 17 patients (17/100, 17%)--7 overgrowth, 6 stent migration, 2 stent degradation, and 2 severe pain. Major complications were 2 hemorrhage, 2 severe pain, and 1 tracheal compression (5/100, 5%), and minor complications were 10 retrosternal pain and 7 symptomatic gastroesophageal reflux (17/100, 17%). After a median follow-up of 142 days, 97 patients had expired. There was no stent-related mortality or 30-day mortality.



CONCLUSION: The fully covered, retrievable Niti-S stent has proved its effectiveness for palliation of malignant dysphagia and feasibility of endoscopic retrieval. We estimate its dog-bone shaped flanges at both ends and it being completely covered provide good resistance to migration and overgrowth.
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dc.language.isoen-
dc.subject.MESHAged-
dc.subject.MESHConstriction, Pathologic-
dc.subject.MESHDevice Removal-
dc.subject.MESHEsophageal Neoplasms-
dc.subject.MESHEsophagus-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHLung Neoplasms-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPalliative Care-
dc.subject.MESHProspective Studies-
dc.subject.MESHProsthesis Failure-
dc.subject.MESHRecurrence-
dc.subject.MESHStents-
dc.subject.MESHStomach Neoplasms-
dc.titleFully covered, retrievable self-expanding metal stents (Niti-S) in palliation of malignant dysphagia: long-term results of a prospective study.-
dc.typeArticle-
dc.identifier.pmid21557717-
dc.identifier.urlhttp://informahealthcare.com/doi/abs/10.3109/00365521.2011.571706-
dc.contributor.affiliatedAuthor김, 진홍-
dc.contributor.affiliatedAuthor임, 선교-
dc.contributor.affiliatedAuthor신, 성재-
dc.contributor.affiliatedAuthor이, 기명-
dc.contributor.affiliatedAuthor이, 광재-
dc.type.localJournal Papers-
dc.identifier.doi10.3109/00365521.2011.571706-
dc.citation.titleScandinavian journal of gastroenterology-
dc.citation.volume46-
dc.citation.number7-8-
dc.citation.date2011-
dc.citation.startPage875-
dc.citation.endPage880-
dc.identifier.bibliographicCitationScandinavian journal of gastroenterology, 46(7-8). : 875-880, 2011-
dc.identifier.eissn1502-7708-
dc.relation.journalidJ000365521-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Gastroenterology
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