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Pulmonary artery pressure in chronic obstructive pulmonary disease without resting hypoxaemia.
DC Field | Value | Language |
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dc.contributor.author | Lee, JH | - |
dc.contributor.author | Oh, YM | - |
dc.contributor.author | Seo, JB | - |
dc.contributor.author | Lee, YK | - |
dc.contributor.author | Kim, WJ | - |
dc.contributor.author | Sheen, SS | - |
dc.contributor.author | Kim, TH | - |
dc.contributor.author | Kim, EK | - |
dc.contributor.author | Lee, JS | - |
dc.contributor.author | Huh, JW | - |
dc.contributor.author | Lim, SY | - |
dc.contributor.author | Yoon, HI | - |
dc.contributor.author | Shin, TR | - |
dc.contributor.author | Lee, SM | - |
dc.contributor.author | Lee, SY | - |
dc.contributor.author | Lee, SD | - |
dc.date.accessioned | 2012-04-23T01:58:59Z | - |
dc.date.available | 2012-04-23T01:58:59Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/6477 | - |
dc.description.abstract | BACKGROUND: Chronic obstructive pulmonary disease (COPD) can lead to pulmonary hypertension and cor pulmonale, which are predictors of mortality.
OBJECTIVE: To identify predictors of increased pulmonary artery pressure (PAP) in COPD patients without resting hypoxaemia, and to characterise COPD patients with increased PAP. DESIGN: A study of 117 COPD patients from the Korean Obstructive Lung Disease (KOLD) cohort who had measurable tricuspid regurgitant flow under transthoracic Doppler echocardiography and no resting hypoxaemia. RESULTS: The mean patient age was 67 years. Mean forced expiratory volume in 1 second (FEV(1)) was 47% predicted, mean haemoglobin (Hb) concentration was 145 g/l and mean systolic PAP (sPAP) was 33 mmHg. Multiple linear regression analysis showed that Hb was the only factor independently associated with sPAP (beta = -1.752, P = 0.005). Cluster analysis using FEV(1)% predicted, sPAP and Hb concentration as variables indicated three patient clusters: Cluster 1 (n = 36; mean FEV(1) 44% predicted, mean sPAP 39 mmHg, mean Hb 132 g/l), Cluster 2 (n = 45; FEV(1) 35% predicted, sPAP 31 mmHg, Hb 154 g/l), and Cluster 3 (n = 36; FEV(1) 65% predicted, sPAP 29 mmHg, Hb 148 g/l). CONCLUSION: Elevated PAP was linked to low haemoglobin levels in COPD without resting hypoxaemia. | - |
dc.language.iso | en | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Anemia | - |
dc.subject.MESH | Anoxia | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Forced Expiratory Volume | - |
dc.subject.MESH | Hemoglobins | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Hypertension, Pulmonary | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Pulmonary Artery | - |
dc.subject.MESH | Pulmonary Disease, Chronic Obstructive | - |
dc.subject.MESH | Questionnaires | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Spirometry | - |
dc.title | Pulmonary artery pressure in chronic obstructive pulmonary disease without resting hypoxaemia. | - |
dc.type | Article | - |
dc.identifier.pmid | 21575307 | - |
dc.identifier.url | http://openurl.ingenta.com/content/nlm?genre=article&issn=1027-3719&volume=15&issue=6&spage=830&aulast=Lee | - |
dc.contributor.affiliatedAuthor | 신, 승수 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.5588/ijtld.10.0598 | - |
dc.citation.title | The international journal of tuberculosis and lung disease | - |
dc.citation.volume | 15 | - |
dc.citation.number | 6 | - |
dc.citation.date | 2011 | - |
dc.citation.startPage | 830 | - |
dc.citation.endPage | 837 | - |
dc.identifier.bibliographicCitation | The international journal of tuberculosis and lung disease, 15(6). : 830-837, 2011 | - |
dc.identifier.eissn | 1815-7920 | - |
dc.relation.journalid | J010273719 | - |
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