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Clinical evaluation of the computerized chronic urticaria-specific quality of life questionnaire in Korean patients with chronic urticaria

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dc.contributor.authorYe, YM-
dc.contributor.authorPark, JW-
dc.contributor.authorKim, SH-
dc.contributor.authorChoi, JH-
dc.contributor.authorHur, GY-
dc.contributor.authorLee, HY-
dc.contributor.authorLee, EH-
dc.contributor.authorPark, HS-
dc.date.accessioned2013-04-24T04:15:58Z-
dc.date.available2013-04-24T04:15:58Z-
dc.date.issued2012-
dc.identifier.issn0307-6938-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/7919-
dc.description.abstractBACKGROUND: Chronic urticaria (CU) is a common skin disorder that affects the well-being and quality of life (QOL) of patients. Recently, we developed and validated a questionnaire for measuring QOL in Korean patients with CU, called the Chronic Urticaria-Specific Quality of Life (CU-QOL) questionnaire.



AIM: To evaluate the clinical significance of a computerized version of the CU-QOL, in adult patients with CU.



METHODS: This was a cross-sectional observational study that enrolled 249 Korean patients with CU from five university hospitals and measured computerized CU-QOL scores and Urticaria Activity Score (UAS) simultaneously. The internal consistency of the computerized CU-QOL was analysed using Cronbach α. To identify clinical correlations between the CU-QOL and patient characteristics, the atopic status and serum autoantibodies, including antinuclear, antithyroglobulin and antimicrosome antibodies, were measured. Multiple linear regression models were used to identify CU-QOL predictors.



RESULTS: Cronbach α was 0.94 for the overall computerized CU-QOL score. The CU-QOL scores correlated significantly with the UAS (r= -0.49, P<0.001). Of the factors aggravating CU, delayed pressure, sunlight exposure and emotional stress significantly influenced the overall CU-QOL scores in the univariate analysis. Multivariate regression models indicated that UAS and emotional stress were significant predictors of the four domains and of the total CU-QOL scores.



CONCLUSIONS: The computerized CU-QOL is a convenient and valid tool for measuring QOL in patients with CU. This study suggests that UAS, dermatographism and emotional stress are strong CU-QOL predictors in Korean patients with CU.
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dc.language.isoen-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAutoantibodies-
dc.subject.MESHChronic Disease-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHHealth Status-
dc.subject.MESHHumans-
dc.subject.MESHKorea-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPsychometrics-
dc.subject.MESHQuality of Life-
dc.subject.MESHQuestionnaires-
dc.subject.MESHRegression Analysis-
dc.subject.MESHSoftware Validation-
dc.subject.MESHUrticaria-
dc.subject.MESHYoung Adult-
dc.titleClinical evaluation of the computerized chronic urticaria-specific quality of life questionnaire in Korean patients with chronic urticaria-
dc.typeArticle-
dc.identifier.pmid22731761-
dc.identifier.urlhttp://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0307-6938&date=2012&volume=37&issue=7&spage=722-
dc.contributor.affiliatedAuthor예, 영민-
dc.contributor.affiliatedAuthor박, 해심-
dc.type.localJournal Papers-
dc.identifier.doi10.1111/j.1365-2230.2012.04414.x-
dc.citation.titleClinical and experimental dermatology-
dc.citation.volume37-
dc.citation.number7-
dc.citation.date2012-
dc.citation.startPage722-
dc.citation.endPage728-
dc.identifier.bibliographicCitationClinical and experimental dermatology, 37(7). : 722-728, 2012-
dc.identifier.eissn1365-2230-
dc.relation.journalidJ003076938-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Allergy
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