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Comparison of off-pump coronary artery bypass grafting with percutaneous coronary intervention versus drug-eluting stents for three-vessel coronary artery disease.
DC Field | Value | Language |
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dc.contributor.author | Yi, G | - |
dc.contributor.author | Youn, YN | - |
dc.contributor.author | Yoo, KJ | - |
dc.contributor.author | Hong, YS | - |
dc.date.accessioned | 2010-12-29T05:23:06Z | - |
dc.date.available | 2010-12-29T05:23:06Z | - |
dc.date.issued | 2008 | - |
dc.identifier.issn | 0003-4975 | - |
dc.identifier.uri | http://repository.ajou.ac.kr/handle/201003/901 | - |
dc.description.abstract | BACKGROUND: Drug-eluting stents (DESs) have challenged coronary bypass grafting as the gold standard for 3-vessel coronary artery disease. This study compared the clinical results between percutaneous intervention with DESs vs off-pump coronary bypass surgery (OPCAB).
METHODS: The study included 388 matched patients with 3-vessel coronary artery diseases who were treated either with DESs or OPCAB. We compared 30-day, 12-month, and cumulative major adverse cardiac and cerebrovascular events (MACCE) during the follow-up. RESULTS: The overall follow-up was 98.5%. Follow-up duration was 621.1 +/- 259.9 days (range, 13 to 1117 days). The rates of MAACE in the DES and OPCAB group were, respectively, 1.5% at 30 days (p = 0.315) and 9.8% and 3.6% at 12 months (p = 0.015). During follow-up, five deaths occurred in the DES group and one in OPCAB group (p = 0.1). Three-year survival rate was 95.1% +/- 2.9% in DES group and 99.5% +/- 0.5% in OPCAB group (p = 0.075). Survival free from MACCE at 3 years was 73.3% +/- 5.3% in DES group and 91.3% +/- 2.9% in OPCAB group (p < 0.001). The major event for the differences between the groups was target vessel revascularization (p < 0.001): 21 DES patients (10.8%) vs 6 OPCAB patients (3.1%). CONCLUSIONS: OPCAB showed better clinical outcome in 12-month and cumulative MACCE rate in 3-vessel coronary artery diseases. The major factor for the difference was target vessel revascularization. Longer follow-up is needed to clarify the differences between the two groups. | - |
dc.language.iso | en | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary | - |
dc.subject.MESH | Cardiopulmonary Bypass | - |
dc.subject.MESH | Cerebrovascular Disorders | - |
dc.subject.MESH | Coronary Artery Bypass | - |
dc.subject.MESH | Coronary Disease | - |
dc.subject.MESH | Coronary Restenosis | - |
dc.subject.MESH | Drug-Eluting Stents | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myocardial Revascularization | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Survival Analysis | - |
dc.subject.MESH | Treatment Outcome | - |
dc.subject.MESH | Vascular Patency | - |
dc.title | Comparison of off-pump coronary artery bypass grafting with percutaneous coronary intervention versus drug-eluting stents for three-vessel coronary artery disease. | - |
dc.type | Article | - |
dc.identifier.pmid | 19049727 | - |
dc.identifier.url | http://linkinghub.elsevier.com/retrieve/pii/S0003-4975(08)01427-6 | - |
dc.contributor.affiliatedAuthor | 홍, 유선 | - |
dc.type.local | Journal Papers | - |
dc.identifier.doi | 10.1016/j.athoracsur.2008.07.040 | - |
dc.citation.title | The Annals of thoracic surgery | - |
dc.citation.volume | 86 | - |
dc.citation.number | 5 | - |
dc.citation.date | 2008 | - |
dc.citation.startPage | 1438 | - |
dc.citation.endPage | 1443 | - |
dc.identifier.bibliographicCitation | The Annals of thoracic surgery, 86(5). : 1438-1443, 2008 | - |
dc.identifier.eissn | 1552-6259 | - |
dc.relation.journalid | J000034975 | - |
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