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Comparison of off-pump coronary artery bypass grafting with percutaneous coronary intervention versus drug-eluting stents for three-vessel coronary artery disease.

DC Field Value Language
dc.contributor.authorYi, G-
dc.contributor.authorYoun, YN-
dc.contributor.authorYoo, KJ-
dc.contributor.authorHong, YS-
dc.date.accessioned2010-12-29T05:23:06Z-
dc.date.available2010-12-29T05:23:06Z-
dc.date.issued2008-
dc.identifier.issn0003-4975-
dc.identifier.urihttp://repository.ajou.ac.kr/handle/201003/901-
dc.description.abstractBACKGROUND: Drug-eluting stents (DESs) have challenged coronary bypass grafting as the gold standard for 3-vessel coronary artery disease. This study compared the clinical results between percutaneous intervention with DESs vs off-pump coronary bypass surgery (OPCAB).



METHODS: The study included 388 matched patients with 3-vessel coronary artery diseases who were treated either with DESs or OPCAB. We compared 30-day, 12-month, and cumulative major adverse cardiac and cerebrovascular events (MACCE) during the follow-up.



RESULTS: The overall follow-up was 98.5%. Follow-up duration was 621.1 +/- 259.9 days (range, 13 to 1117 days). The rates of MAACE in the DES and OPCAB group were, respectively, 1.5% at 30 days (p = 0.315) and 9.8% and 3.6% at 12 months (p = 0.015). During follow-up, five deaths occurred in the DES group and one in OPCAB group (p = 0.1). Three-year survival rate was 95.1% +/- 2.9% in DES group and 99.5% +/- 0.5% in OPCAB group (p = 0.075). Survival free from MACCE at 3 years was 73.3% +/- 5.3% in DES group and 91.3% +/- 2.9% in OPCAB group (p < 0.001). The major event for the differences between the groups was target vessel revascularization (p < 0.001): 21 DES patients (10.8%) vs 6 OPCAB patients (3.1%).



CONCLUSIONS: OPCAB showed better clinical outcome in 12-month and cumulative MACCE rate in 3-vessel coronary artery diseases. The major factor for the difference was target vessel revascularization. Longer follow-up is needed to clarify the differences between the two groups.
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dc.language.isoen-
dc.subject.MESHAngioplasty, Balloon, Coronary-
dc.subject.MESHCardiopulmonary Bypass-
dc.subject.MESHCerebrovascular Disorders-
dc.subject.MESHCoronary Artery Bypass-
dc.subject.MESHCoronary Disease-
dc.subject.MESHCoronary Restenosis-
dc.subject.MESHDrug-Eluting Stents-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHKaplan-Meier Estimate-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMyocardial Revascularization-
dc.subject.MESHRecurrence-
dc.subject.MESHSurvival Analysis-
dc.subject.MESHTreatment Outcome-
dc.subject.MESHVascular Patency-
dc.titleComparison of off-pump coronary artery bypass grafting with percutaneous coronary intervention versus drug-eluting stents for three-vessel coronary artery disease.-
dc.typeArticle-
dc.identifier.pmid19049727-
dc.identifier.urlhttp://linkinghub.elsevier.com/retrieve/pii/S0003-4975(08)01427-6-
dc.contributor.affiliatedAuthor홍, 유선-
dc.type.localJournal Papers-
dc.identifier.doi10.1016/j.athoracsur.2008.07.040-
dc.citation.titleThe Annals of thoracic surgery-
dc.citation.volume86-
dc.citation.number5-
dc.citation.date2008-
dc.citation.startPage1438-
dc.citation.endPage1443-
dc.identifier.bibliographicCitationThe Annals of thoracic surgery, 86(5). : 1438-1443, 2008-
dc.identifier.eissn1552-6259-
dc.relation.journalidJ000034975-
Appears in Collections:
Journal Papers > School of Medicine / Graduate School of Medicine > Thoracic & Cardiovascular Surgery
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