The pathophysiology of complex regional pain syndrome is still unkown. Implantation of spinal cord stimulator is generally considered to be a safe and effective procedure. The reported complications are generally minor without serious neurologic deficit. A 21-year-old male patient with CRPS in the right foot had undergone spinal cord stimulator implantation. After the surgery, spinal epidural hemorrhage occurred and he became paraplegic. After spinal cord injury, symptoms of CRPS disappeared. This supports the hypothesis of spinal neuronal sensitization. This case would help to understand pathophysiology of CRPS development.